I have struggled with waking up in the middle of the night between 2:00 am and 3:00 am for as far back as my early twenties. AUTHOR Terri DeNeui, DNP, APRN, ACNP-BC CATEGORY Hair Transplant SOCIAL @EVEXIASMEDICAL Back then you just think it's the crazy schedule and in my thirties I figured it was having babies, but when you hit your forties and realize you're not going to make it without sleep - you start to pay closer attention. I have low blood sugar issues and I will often wake in the middle of the night if I go to bed not eating something well balanced. Adrenal and stress is also a factor since stress hormones will initiate low blood sugar. The most overlooked issue related to waking in the middle of the night is the liver.
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